Small‐scale field evaluation of the entomological efficacy and the residual activity of Fludora ^® Fusion WP‐SB indoor residual spraying against <i>Anopheles culicifacies s.l</i> . in Gujarat, India

Objectives To evaluate the entomological efficacy and residual activity of indoor spraying with Fludora® Fusion 562.5 WP-SB, a combination formulation containing clothianidin, neonicotinoid deltamethrin, pyrethroid, against main rural malaria vector, Anopheles culicifacies s.l., in India small-scale trial. Methods In three study villages, suitable households were randomly allocated to five treatments: WP-SB (target dose 225 mg active ingredient AI/m2); clothianidin 70 WG 200 K-Othrine 250 (deltamethrin, target 25 Ficam VC 80 (bendiocarb, 400 AI/m2) unsprayed control. Insecticides sprayed by hand compression sprayers control flow valves 8002E nozzles. Post-spray cone bioassays done on insecticide-treated walls using colonised, deltamethrin-resistant strain An. culicifacies. Mosquitoes collected from treated rooms different methods. The insecticide content filter papers was determined chemical assay assess spray quality. Results ratios applied doses insecticides within 0.84 1.4, showing good revealed action lasting 7 months for all without significant differences mortality between surfaces nor four treatment arms (P > 0.05). Considering parameters such as resting density, excito-repellency, blood-feeding inhibition delayed mortality, overall WG-SB equal or better compared other insecticides. Conclusions showed than deltamethrin bendiocarb alone pyrethroid-resistant vector population can be considered an alternative product management pyrethroid resistance vectors.